Support and Resources through the Nobelpharma Connect Program

Getting Started

Nobelpharma Connect is designed to support patients throughout every stage of their treatment journey. Our comprehensive patient support portal offers a range of resources and services to help you with access and information related to your insurance benefits and costs. Explore the link below and talk to your doctor about which program is right for you.

To get started, visit today or call 1-877-649-3867 during the hours of 8:00 a.m. to 6:00 p.m. ET, Monday through Friday.


Select from all currently available resources for HYFTOR® below:

Additional Resources

Some other helpful organizations, links, and information: 

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Talking to Your Doctor

You and your doctor should always discuss the best treatment options for you.

Ask your doctor if HYFTOR® could help you treat your facial angiofibroma and discuss when you may be able to start.

Frequently Asked Questions

Getting Support

Our Patient Support Program shares educational materials to help you on your treatment journey.

Getting Access

We are committed to helping you get your prescription for HYFTOR as simply and seamlessly as possible. Patient support can help with:  

  • Insurance verification 
  • Prior authorization facilitation 
  • Enrollment in our reimbursement program 
  • Refill reminders  


Download our Patient Support Program Fact Sheet to see everything we can do to help as you start your treatment journey with HYFTOR. 

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Stay Up To Date

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Important Safety Information

What is HYFTOR®?
HYFTOR® is a prescription medicine that is used on the skin (topical) to treat adults and children 6 years of age and older with a type of noncancerous tumor called angiofibroma on your face caused by the genetic condition tuberous sclerosis.
It is not known if HYFTOR® is safe and effective in children under 6 years of age.
Important: HYFTOR® is for use on the skin only (topical use). Do not use HYFTOR® in your mouth, eyes, or vagina.
Do not use HYFTOR® if you are allergic to sirolimus or any of the other ingredients in HYFTOR®.

Before using HYFTOR®, tell your healthcare provider about all of your medical conditions, including if you:

  • have a skin infection at the treatment site
  • have high cholesterol or high triglycerides (fat or lipids) in your blood
  • are scheduled to receive an immunization (vaccine). You should avoid receiving live vaccines during treatment with HYFTOR®. Vaccines may be less effective during treatment with HYFTOR®.
  • are pregnant or plan to become pregnant. HYFTOR® may harm your unborn baby. You should not become pregnant during treatment with HYFTOR®.
    • Females who are able to become pregnant should use effective birth control (contraception) before starting treatment with HYFTOR®, during treatment, and for 12 weeks after your final dose of HYFTOR®. Talk to your healthcare provider about types of birth control that you can use during this time.
  • are breastfeeding or plan to breastfeed. It is not known if HYFTOR® passes into your breast milk. You should not breastfeed during treatment with HYFTOR®.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What should I avoid while using HYFTOR®?
Limit your exposure to sunlight and artificial light, such as tanning beds and ultraviolet light therapy, during treatment with HYFTOR®. Wear clothing that covers your skin if you need to go outside. Talk with your healthcare provider about other ways you can protect your skin from the sun.

What are possible side effects of HYFTOR®? HYFTOR® may cause serious side effects, including:

  • Allergic reactions. Serious allergic reactions have happened in people who have taken sirolimus by mouth. Stop using HYFTOR® and get medical help right away if you get any of these symptoms: swelling of your face, eyes, or mouth, trouble breathing or wheezing, throat tightness, chest pain or tightness, feeling dizzy or faint, rash or peeling of your skin.
  • Serious infections, including infections that can happen when your immune system is weak, have happened in people who have taken sirolimus by mouth. Some people have developed a rare, serious brain infection called progressive multifocal leukoencephalopathy (PML) which can sometimes cause death. Stop using HYFTOR® and call your healthcare provider right away if you get symptoms of an infection including fever or chills.
  • Risk of cancer. Lymphoma and other cancers, especially skin cancer, have happened in people who have taken sirolimus by mouth. Talk with your healthcare provider about your risk for cancer if you use HYFTOR®.
  • Increased levels of cholesterol and triglycerides (fat or lipids) in the blood have happened in people who have taken sirolimus by mouth. Your healthcare provider will treat you for high lipid levels, if needed.
  • Lung or breathing problems. Lung or breathing problems, including problems that have sometimes caused death, have happened in people who have taken sirolimus by mouth. Stop using HYFTOR® and get medical help right away if you get symptoms such as shortness of breath, new or worsening cough, or chest pain.
The most common side effects of HYFTOR® include dry skin, application site irritation, itching, acne, acne-like rash, eye redness, skin bleeding, and skin irritation.
HYFTOR® may cause fertility problems in males and females, which may affect your ability to have children. Talk to your healthcare provider if this is a concern for you.
These are not all the possible side effect of HYFTOR®, Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see 
Patient Information for additional safety information. 
You are encouraged to report side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088. You may also reach out to Nobelpharma America, LLC at 1-877-375-0825

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